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However, this single-pathway activation proves insufficient for patients whose weight regulation depends more heavily on GIPR signaling, MC4R pathways, or FTO genetic variants that increase appetite set-point
TripleHormone-Receptor Agonist Retatrutide for Obesity (NCT04881760)
Be prepared to follow up if needed
This difference in hormonal activity may lead to slightly different metabolic effects and weight loss responses
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